Antibody Isolation

Antibody purification and isolation require tightly controlled microenvironments with robust chemical compatibility and microfluidic systems with high surface-area-to-volume ratios.

FEMTOPRINT’s glass chips offer inert, stable platforms for affinity chromatography, filtration, and reaction steps.

We solve:

• Channel degradation with harsh buffers or solvents
• Unwanted molecule adsorption on polymer surfaces
• Reproducibility issues in hand-assembled purification modules

You gain:

• True 3D microfluidic layouts with integrated capture zones
• High-resolution pillar structures for surface area control
• Autoclavable, reusable glass components
• Controlled surface chemistry for high-binding efficiency.
• Low nonspecific adsorption for pure yields.
• Scalable designs for process intensification

Contact our expert for your next microfluidic project.

Applications in antibody workflows

Glass microfluidic chips support affinity capture, antibody purification, immunoassays and continuous-flow separation in biopharma R&D and diagnostics, where chemical inertness and reproducible surface chemistry are essential.

Frequently asked questions

Why glass microfluidics for antibody isolation?
Glass provides inert, low-fouling surfaces and high surface-area-to-volume microchannels, improving binding efficiency and reproducibility versus polymer chips.

Can the chips be functionalized for affinity capture?
Yes. The glass surface can be functionalized for antibody-antigen affinity chemistry while maintaining optical clarity for integrated detection.

Related life sciences applications: Discover more femtosecond laser glass micromachining solutions for life sciences, including Diagnostics, Cell Therapies, and Bio-Chemical Sensing.