Single Cell Analysis

Unlocking Cellular Heterogeneity, One Cell at a Time

Single-cell research demands micron-scale features and optical transparency to capture and analyze individual cells with high fidelity. Isolating and analyzing single cells demands ultra-precise microstructures with minimal dead volume. Our micromanufacturing technology delivers ultra-fine 3D structures with embedded fluidics, waveguides, and chambers in one monolithic glass chip.

We solve:

• Misalignment between micro-optics and microfluidics
• Poor visibility through polymer devices
• Inadequate resolution of conventional fabrication methods

You gain:

• Sub-micron precision in traps, channels, and wells
• High-resolution features for reliable cell trapping and sorting.
• Built-in optical paths for single-cell detection or manipulation
• Rigid glass platforms for stable long-term studies
• Optical transparency for fluorescence and microscopy applications
• Low autofluorescence for clean signal detection

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Applications in single-cell analysis

Glass microfluidic chips enable single-cell capture, isolation, sorting and optical interrogation for genomics, transcriptomics and drug-response studies, where micron-scale features and optical transparency are critical.

Frequently asked questions

Why glass for single-cell analysis devices?
Glass combines high optical clarity, low autofluorescence and precise micron-scale channels, enabling accurate capture and imaging of individual cells.

Can trapping structures be integrated with optics?
Yes. Cell-trapping microstructures can be integrated with micro-lenses and waveguides in one glass chip for combined manipulation and detection.

Related life sciences applications: Discover more femtosecond laser glass micromachining solutions for life sciences, including Diagnostics, Cell Therapies, and Antibody Isolation.