Bio-Chemical Sensing

Reliable biosensors need microfluidic chips with precise surface functionalization and minimal interference. In addition, biosensors and chemical sensors require exact control of light-matter interaction.

Our technology enables 3D integration of microfluidic channels, mirrors, and fiber alignment grooves in a single chip.

We solve:

• Material incompatibilities that limit sensor design
• Optical losses due to component misalignment
• Poor repeatability of manual assembly

You gain:

• Seamless optical path integration
• Tailored reaction chambers for ultra-low volume sensing
• Ready-for-packaging glass chips for compact analyzers
• Low non-specific binding for cleaner detection.
• Compatibility with surface modifications (e.g., antibodies, aptamers).
• Long-term stability under varying pH and temperature conditions

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Applications of glass biosensors and chemical sensors

Integrated glass biochemical sensing platforms support point-of-care diagnostics, environmental and water-quality monitoring, food and pharmaceutical quality control, and label-free optical detection based on refractive-index, fluorescence and absorbance measurements.

Frequently asked questions

Why use glass for biochemical sensing chips?
Glass offers optical transparency, chemical inertness and biocompatibility, allowing microfluidic channels, mirrors and fiber-alignment grooves to be integrated monolithically for high sensitivity and low optical loss.

Can optical and fluidic functions be combined on one chip?
Yes. Femtosecond-laser 3D microfabrication integrates microfluidics and micro-optics in a single glass substrate, reducing assembly steps and improving signal-to-noise for sensitive detection.

Related life sciences applications: Discover more femtosecond laser glass micromachining solutions for life sciences, including Diagnostics, Antibody Isolation, and Single Cell Analysis.